New research suggests a need for guidelines around the storage and dosing for hyaluronidase (HYAL) when using hyaluronic acid (HA) fillers.

"Hyaluronic acids continue to be the fillers of choice worldwide and their popularity is growing," the authors wrote in Aesthetic Surgery Journal. "Adverse events (AEs) are able to be resolved through the use of HYAL. However, routine HYAL use has been at issue due to perceived safety issues."

The researchers noted that there are currently no established guidelines for HYAL use in aesthetic procedures, leading to inconsistent practices in storage, preparation, skin testing, and adverse event management. Their study utilized a 39-question survey about HYAL usage (completed by 264 healthcare practitioners: 244 from selected databases and 20 from a consensus panel). Responses from the database group were compared with those from the consensus panel.

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Review the study in full in Aesthetic Surgery Journal >>