Study Reveals Botulinum Toxin Complication Rates at 16%

Posted By American Med Spa Association, Thursday, May 5, 2022

A review of complication rates following botulinum toxin A (BoNT-A) injections in the glabellar region and forehead found that 16% of patients experience adverse events, including headache, local skin reactions and facial neuromuscular symptoms.

For their study, published in the May 2022 issue of the Aesthetic Surgery Journal, David Zargaran, MBBS, BSc, et al, searched MEDLINE and EMBASE for studies reporting complications after cosmetic BoNT-A in the glabellar or in the forehead region. Of 556 identified articles, 24 were included in the final quantitative analysis, with 4,268 BoNT-A injection sessions and 1,234 placebos.

The most frequently observed treatment-related complications in the BoNT-A groups included headache, local skin reactions and facial neuromuscular symptoms with an overall BoNT-A complication rate of 16%.

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