Cosmetic surgeons can use relatively low volumes of a 20-mg/mL, smooth,highly cohesive, viscous hyaluronic acid (HA) filler to correct mid-face volume loss, with high rates of patient satisfaction — even at 12 months after injection, according to a newly published study. 
“The study findings suggest that, in daily practice, physicians can provide appropriately selected patients with long-lasting, cost-effective correction using small volumes of this HA filler,” the study’s lead author Monique Wilson, M.D., a dermatologist at Cosmetic Laser Dermatology in San Diego, tells Cosmetic Surgery Times. For reference, the pivotal aproval trial used mean injection volume of 6.65 mL, a large and perhaps unrealistic volume in many practices.