In medical aesthetics, transdermal devices, or penetration enhancers, that use microneedles, rollers, dermoelectroporation and other novel modalities offer practitioners an efficient and minimally invasive technique to penetrate the skin barrier. But while practitioners have eagerly embraced these products and devices, few therapeutic or regulatory standards exist.

Physicians initially used these systems for skin rejuvenation procedures; however, after years of refinement, the devices now address many indications, such as acne scars and other scar types, hair loss, cellulite, fine lines and wrinkles, pigmentary problems, axillary hyperhidrosis, actinic keratosis in photodamaged skin, skin tightening and more.

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